Azitra

Vision

Harnessing the microbiome to treat skin disease.

Approach

Azitra Inc. is a clinical-stage medical dermatology company that leverages extensive scientific knowledge about the skin microbiome to discover and develop novel products for the treatment of adverse skin conditions and diseases. The Company’s technology platform, developed in collaboration with scientists at Yale University and the Jackson Laboratory, is based on a proprietary strain of the natural commensal bacteria Staphylococcus epidermidis. Direct application of these commensal bacteria alone improves skin appearance, hydration, and healing. These bacteria can also be designed to become effective therapies using the tools of genetic engineering. Many diseases, including ichthyosis vulgaris and orphan diseases such as Netherton syndrome, are the result of deficient or missing proteins in the skin. We have engineered commensal skin bacteria to deliver these missing, critical proteins directly to the target through the stratum corneum of the skin, resolving the underlying disease cause and returning the microbiome to a more normal state.

Azitra (AZTR) went public in June 2023.

Azitra is addressing

• Leap 06 / Reverse autoimmune diseases and chronic inflammation